![]() ![]() mirabilis strains belonged to the IPM family, and three others belonged to the VIM family. Seven cases of bacteremia, including 3 intravascular catheter related, one surgical site infection, and one urinary tract infection were identified. The outbreak was discovered in June and expanded rapidly ten of twelve (83%) patients in ICU were colonized with outbreak strains in July. These isolates exhibited multi-drug resistance. From June through November, 2008, nine patients in the surgical ICU were infected by MBL-producing P. In July and in November 2008, we conducted a point prevalence survey of rectal colonization with MBL-producing P. We used a multiplex PCR assay to detect and differentiate each of the MBL gene families: IPM, VIM, SPM, GIM and SIM. All enterobacterial isolates from clinical specimens (one per patient) were tested for MBL production. mirabilis isolates were reviewed retrospectively. Records from patients in this ICU who had MBL-producing P. We described an emerging outbreak of infection caused by metallo-ß-lactamase (MBL)-producing Proteus mirabilis that occurred in the surgical ICU of a Serbian university hospital, and assessed this outbreak in a retrospective observational study. Piperacillin/Tazobactam is the candidate drug to start in children with septicemia and suspected ESBL or carbapenemase-producing E. coli is SHV whereas for carbapenemase-producing E. coli IMP was the most frequent, its sensitivity was high to Piperacillin/Tazobactam and Ciprofloxacin (52.6% each). coli was SHV, it was more sensitive to Piperacillin/Tazobactam (90%) and cefepime (86.7%) while for carbapenemase-producing E. The most frequently detected gene of ESBL producing E. Neither risk factors for infection nor clinical picture can differentiate between ESBL and carbapenemase producing E. Of 88 patients with sepsis, 49 and 30 strains were ESBL producing and carbapenemase producing E. The initial results were measured through the 30-days of hospital admission. Bacterial susceptibility to antibiotics was tested. Polymerase chain reaction for ESBL and carbapenemase producing E. coli were isolated on double disk diffusion and EDTA double disk, respectively. ![]() coli were identified by Gram stain and biochemically by the Microscan automated system. This is a cross-sectional study performed on 88 patients with sepsis. coli isolates from infants and children with septicemia and to identify their antibiotic sensitivity pattern. To detect the prevalence of Extended-Spectrum Beta-Lactamase (ESBL) and carbapenemase-genes between E. Coli) is a leading cause of death of infants and children in intensive care units. Treatment failure of sepsis caused by Escherichia coli ( E. ![]()
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